Research in Crohn’s disease shows peripheral blood T cells are already less prone to apoptosis before reaching the gut, with reduced catalase activity contributing to this effect 🧬
@ceijournal.bsky.social
@ceijournal.bsky.socialResearch in Crohn’s disease shows peripheral blood T cells are already less prone to apoptosis before reaching the gut, with reduced catalase activity contributing to this effect 🧬
@aegeanconf.bsky.social🧬 Welcome to Crete! 🇬🇷
Join us tomorrow for the 1st International Conference on T Cells in Health and Disease!
📋 Registration: 6:00 PM
🥂 Welcome Dinner Reception to follow!
🔗 aegeanconferences.org/conferences/...
#TCells #Immunology
@imtadvances.bsky.socialNew research shows that adding CD28 signalling motifs to the CD3ζ chain boosts IL‑2 production and expansion of TCR‑engineered T cells, without reducing cytotoxicity. A promising step toward stronger TCR therapies for solid tumours.
Read here: vist.ly/5jcu9
@hkoohy.bsky.socialVery honoured to be hosting Prof @kischober.bsky.social at Unravelling T cell recogition webinar series @imm.ox.ac.uk Kilian will present his latest work exploring how EBV-reactive T cells may contribute to CNS autoimmunity in multiple sclerosis. Join me.
#TCells #Immunology #MultipleSclerosis #EBV
@dctomaz.bsky.social🧬 T-cell gene switches can follow cellular state: a new promoter toolkit showed reversible responses in preclinical models. Clinical benefit remains untested. doi.org/10.1038/s414... #Immunology #Tcells
@lsajournal.orgProximity labeling reveals ZFP36L1 as a central hub for post-transcriptional regulatory networks in T cells.
#Immunology #TCells
@sanquin-forlife.bsky.social @oncodeinstitute.bsky.social @monikawolkers.bsky.social
www.life-science-alliance.org/content/9/11...
@jem.orgUpper respiratory tract #CD8⁺ tissue resident memory #Tcells protect against viral transmission. New study from Sarah E. Michalets, Jacob E. Kohlmeier and colleagues (Emory University):
rupress.org/jem/article/...
@vaccinologist.bsky.socialNew Icahn School of Medicine at Mount Sinai study shows that a subset of #pancreaticcancer cells can create fibrin-rich immune-protective niches via PAI1/PAI2, recruiting suppressive macrophages & excluding #Tcells - a new angle for pancreatic #cancer #immunotherapy www.linkedin.com/posts/drmelv...
@castltrastondrs.medsky.network@mayoclinic.org While circulating antibodies (which stop you from getting a mild cold or asymptomatic infection) drop sharply by month 4, your immune system’s B-cells and #Tcells do not wane at the same rate. Because of this deeper cellular memory,
www.mayoclinic.org/diseases-con...
@amjtransplant.bsky.socialCheck out, "Circulating T cell-specific extracellular vesicles as biomarkers of acute cellular rejection after lung transplantation," by Korutla et al in our Sept. issue!
doi.org/10.1016/j.aj...
#LungTransplantation #TransplantRejection #Biomarkers #ExtracellularVesicles #TCells
@rupress.orgIn @jem.org, Michalets et al. demonstrate that upper respiratory tract tissue-resident memory #CD8⁺ T cells are sufficient to protect against respiratory virus transmission, even in the absence of #CD4 #Tcells, #Bcells, or lower respiratory tract immune responses. rupress.org/jem/article/...
@jem.orgMichalets, Kohlmeier et al. demonstrate that upper respiratory tract tissue-resident memory #CD8⁺ T cells are sufficient to protect against respiratory virus transmission, even in the absence of #CD4 #Tcells, #Bcells, or lower respiratory tract immune responses. rupress.org/jem/article/...
@immunologypodcast.com🎤 Next episode has dropped!
Dr. Martin Prlic at @fredhutch.org joins us on the podcast to talk about how #TCells behave and adapt across healthy, inflamed, and diseased human tissues.
🎧 Tune in now: https://bit.ly/4qLZ8A0
@jem.orgFunctional heterogeneity and plasticity in naïve #CD8 #Tcells drive superior effector and memory responses. New study from Yamato Sajiki, Koichi Araki and colleagues @cincyresearch.bsky.social:
rupress.org/jem/article/...
@amjtransplant.bsky.socialIntroducing our new feature, AJT Catalyst!
www.amjtransplant.org/catalyst
This month, read "The Art and TCRAFT of T cell recognition" by AF Sharland and NM Rogers
authors.elsevier.com/a/1nWHu5hx-W...
#TCells #TCellRecognition #Immunology #TCellBiology #TransplantImmunology
@aging-us.bsky.social✅ Read our #Blog post about the #Research paper, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."
#Summary ⬇️
https://bit.ly/4gW9f2w
#Aging #HIV #COVID #Tcells #OA #PeerReviewed #Journal #Publishing #MedEd