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@longevitytech.bsky.socialOct 1, 2026, 11:25 AM

Allergan Aesthetics is pairing new hallmarks-of-aging science with real skin data from people on weight-loss drugs.

Link as first comment.

#longevity #geroscience #aging #skincare #weightloss

A tool applies a liquid to skin in a longevity treatment.
@longevitytech.bsky.socialSep 30, 2026, 2:18 PM

Dr Sean Leng and the Johns Hopkins-SunInflam team land a $1 million XPRIZE Healthspan Milestone 2 award for aging research.

Link as first comment.

#longevity #geroscience #XPRIZE #healthspan #agingresearch

Digital and human hands reaching out, Johns Hopkins logo, XPRIZE text.
@longevitytech.bsky.socialSep 30, 2026, 1:14 PM

LW-1017, an oral drug that switches the brain’s cleanup system back on, reduced Parkinson’s and Alzheimer’s pathology in aged mouse models.

Link as first comment.

#longevity #geroscience #LW1017 #parkinsons #alzheimers

Colorful 3D model of a drug interacting with a cell.
@glf-2026.bsky.socialSep 30, 2026, 6:17 AM

#GLF 2027 Registration Extended!

October 30, 2026
Miami, USA | Hybrid
February 10–11, 2027

Join global experts shaping the future of longevity and healthy aging.

🔗 Register Now: longevityfederation.com/registrations/

#Longevity #HealthyAging #Geroscience #PrecisionHealth #AntiAging

@longevitytech.bsky.socialSep 29, 2026, 3:32 PM

Resolution Therapeutics has treated its last EMERALD trial patient, putting macrophage-based therapy on track for results before year’s end.

Link as first comment.

#longevity #geroscience #macrophage #celltherapy #clinicaltrial

Glass liver model next to a blister pack of pills with text overlay.
@longevitytech.bsky.socialSep 28, 2026, 12:27 PM

The Oxford biotech will present new mouse data on MTRX31, a drug it says works on how cells use fuel rather than on appetite.

Link as first comment.

#longevity #geroscience #MTRX31 #metabolism #biotech

Abstract illustration with red circles and blue squares connected by a mitochondria-like design.
@longevitytech.bsky.socialSep 28, 2026, 11:25 AM

Telomir’s oncology compound helped fish with age-related retinal damage see better and moved two aging-linked markers toward normal.

Link as first comment.

#longevity #geroscience #retinalhealth #aging #telomeres

Group of zebrafish swimming underwater with text overlay.
@longevitytech.bsky.socialSep 28, 2026, 10:18 AM

Coya Therapeutics hits its 100th ALS trial enrollment and publishes new preclinical data, both pointing to the same immune-cell mechanism.

Link as first comment.

#longevity #geroscience #ALS #immunecells #preclinical

People enter a room labeled 'Clinical Trial' as a hand holds a counter showing 100.
@aging-us.bsky.socialSep 27, 2026, 12:00 AM

🧬 Longevity & Aging Series (S3, E6):
Girish Harinath from AgelessRx discusses “Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results.”

🎥 https://www.youtube.com/watch?v=7-NvskI8Ve0

#interview #aging #rapamycin #geroscience #longevity #healthspan #series #meded

@alicefrolov.bsky.socialSep 26, 2026, 5:07 PM

Circulating rejuvenative and stress factors diverge with age: a visualization of simulated plasma trajectories

#HeterochronicParabiosis #GDF15 #GDF11 #Klotho #SystemicFactors #Geroscience #CirculatingProteome #IntegratedStressResponse

Circulating rejuvenative and stress factors diverge with age: a visualization of simulated plasma trajectories I am sharing a figure from an ongoing conceptual modeling exercise examining the age-dependent rebalancing of systemic humoral factors implicated in heterochronic parabiosis and circulating proteome studies. The chart title, "Circulating rejuvenative and stress factors diverge with age," reflects the central hypothesis: that the plasma milieu shifts from a net pro-youthful to a net pro-aging composition across the lifespan. The visualization employs a diverging lollipop-slope hybrid, with paired age-anchored connectors linking young-adult and aged reference points for each analyte. Pro-youthful mediators (GDF11, klotho, oxytocin) are plotted against pro-aging signals (GDF15, CCL11/eotaxin-1, B2M). The connector slope encodes the direction and magnitude of the simulated concentration change, allowing direct visual contrast between the declining anti-geronic arm and the ascending stress-associated arm. I want to state explicitly that the underlying data are simulated. Trajectory parameters were specified to be consistent with directional trends reported in the literature — for instance, the progressive elevation of GDF15 as a mitochondrial integrated stress response marker signaling through GFRAL-RET, the age-associated decline in soluble klotho, and the reported accumulation of B2M and CCL11 with reduced neurogenic and regenerative capacity. The GDF11 axis is presented with appropriate caution given the well-documented assay cross-reactivity with myostatin/GDF8 and the unresolved debate regarding its directionality. The figure is intended as a heuristic scaffold for discussion rather than as an empirical result. I would welcome commentary on whether a normalized effect-size axis or log-fold representation would better accommodate the divergent dynamic ranges of these analytes, and on candidate mediators worth incorporating.
@longevitytech.bsky.socialSep 25, 2026, 7:42 PM

New patent covers combining hTERT and Follistatin-344 to target telomere length, muscle mass and blood-glucose levels in age-related disease.

Link as first comment.

#longevity #geroscience #hTERT #Follistatin344 #telomeres

Illustration of a chromosome tied with a belt and strands, with text: BioViva patents dual-gene approach to aging.
@americanaging.bsky.socialSep 25, 2026, 7:20 PM

Calling AGE trainees! LRC's Fall 2026 Journal Club on Epigenetics & Aging kicks off week of Oct 12 — 3 biweekly sessions, present just 1 key figure, open to grad students/postdocs/early-career researchers everywhere 🧬📚
Sign up: docs.google.com/forms/d/e/1F...

#AGETrainees #GeroScience

@longevitytech.bsky.socialSep 25, 2026, 6:32 PM

Alzheon’s peer-reviewed data tie a falling blood marker to slower memory and brain decline in patients taking its daily pill.

Link as first comment.

#longevity #geroscience #alzheimers #biomarkers #neurodegeneration

Illustration of a pill in a blood vessel with red blood cells and fibrils.
@longevitytech.bsky.socialSep 25, 2026, 4:24 PM

Belgian clinical data show Allegro’s nanotech injection Hydrocelin delivers lasting knee osteoarthritis relief from a single shot.

Link as first comment.

#longevity #geroscience #osteoarthritis #nanotech #Hydrocelin

Needle injecting fluid into a knee joint model.
@agingcongress.bsky.socialSep 25, 2026, 6:25 AM

The Hallmarks of Aging show how cellular changes drive aging, including genomic instability, senescence, mitochondrial dysfunction, and stem-cell exhaustion.

Aging-Longevity Expo 2027

📅 Mar 25–27, 2027 | 🇸🇬 Singapore | Hybrid
🌐 agingnlongevity.com

#Longevity #HealthyAging #Geroscience #Healthspan

@longevitytech.bsky.socialSep 24, 2026, 3:32 PM

Seoul biotech’s redesigned method makes circular RNA up to seven times more efficient to build, widening what RNA medicine can treat.

Link as first comment.

#longevity #geroscience #circularRNA #RNA #biotech

Illustration of circular RNA with molecular structures and text overlay.
@longevitytech.bsky.socialSep 24, 2026, 1:14 PM

Phase Ib/IIa data show an experimental antibody cutting severe COPD flare-ups by up to 100% at the highest dose, a signal for aging lungs.

Link as first comment.

#longevity #geroscience #COPD #antibody #aginglungs

Illustration of human lungs with antibody symbol and text overlay.
@longevitytech.bsky.socialSep 24, 2026, 11:25 AM

NKGen presented new clinical data on troculeucel’s potential in Alzheimer’s, Parkinson’s and frontotemporal dementia.

Link as first comment.

#longevity #geroscience #alzheimers #parkinsons #dementia

Colorful digital rendering of cells with text overlay about NK cell therapy.
@longevitytech.bsky.socialSep 24, 2026, 10:18 AM

Integration combines continuous biometrics with multi-omic testing and physician-led care, with an eye on earlier prevention.

Link as first comment.

#longevity #geroscience #biometrics #multiomics #prevention

Silhouette of a woman's head with blue and orange data patterns connecting to each other.
@glf-2026.bsky.socialSep 24, 2026, 6:34 AM

Mid Registration Ends Tomorrow!

Join GLF 2027 and connect with global longevity leaders.

Feb 10–12, 2027 | Miami, USA
In-Person + Virtual

Mid Rate Ends: Sept 25
🔗 longevityfederation.com/registrations/

#GLF2027 #Longevity #AgingResearch #Geroscience #LongevityBiotechnology #Biotech

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