Arm-wise target matching is now available for anchored MAIC in AbangeLabs HTA Studio. https://www.mattheneus.com/editorial/abangelabs-hta-studio-anchored-maic-weighting-strategy-arm-wise-target-matching-2026-10-08 #HTA #MAIC #EvidenceSynthesis

A time-aligned network of 24 studies sharpens comparative treatment evidence in prurigo nodularis. https://www.mattheneus.com/editorial/prurigo-nodularis-time-aligned-treatment-network-2026-10-07 #HTA #NMA #EvidenceSynthesis

Composite stimulation patterns sharpen evidence on postoperative recovery. https://www.mattheneus.com/editorial/pubmed-transcutaneous-electrical-acupoint-stimulation-postoperative-recovery-composite-pattern-2026-10-07 #HTA #EvidenceSynthesis

Korjuny’s UK approval for malignant ascites puts randomised drainage-control evidence in focus. https://www.mattheneus.com/editorial/mhra-korjuny-catumaxomab-malignant-ascites-randomised-paracentesis-2026-10-02 #HTA #RegulatoryAffairs #EvidenceSynthesis

Daily sedation interruption may shorten ventilation and lower mortality, according to a Cochrane review. https://www.mattheneus.com/editorial/cochrane-daily-sedation-interruption-ventilation-mortality-randomised-review-2026-10-07 #HTA #EvidenceSynthesis #HealthEconomics

A $5.85M federal challenge tests automated evidence synthesis against hidden benchmarks for reproducibility. https://www.mattheneus.com/editorial/ahrq-clinical-evidence-synthesis-hidden-benchmark-reproducibility-2026-10-07 #HTA #EvidenceSynthesis #RegulatoryAffairs

Read #WorldEBHCDay blog by @bilalahmadkhan.bsky.social, GM at Pakistan Institute of Living & Learning. A first attempt in learning: from rejected SPARC Award to building #EvidenceSynthesis capacity in Pakistan & publishing a review with #AI literacy, not AI dependency: https://ow.ly/kHFp50ZVbF8

Spain’s patient-involvement protocol turns recruitment and feedback into auditable HTA practice. #HTA #EvidenceSynthesis #RegulatoryAffairs https://www.mattheneus.com/editorial/spain-redets-patient-involvement-monitoring-protocol-49-reports-2026-10-05

EMA has opened an IRIS route for EU-M4all eligibility requests, sharpening how disease-burden evidence enters global-medicine pathways. https://www.mattheneus.com/editorial/ema-eu-m4all-iris-eligibility-disease-burden-evidence-route-2026-08-18 #HTA #RegulatoryAffairs #EvidenceSynthesis

Germany's machine-readable benefit decisions create a reproducible evidence baseline. https://www.mattheneus.com/editorial/g-ba-machine-readable-benefit-decisions-xml-evidence-baseline-2026-10-07 #HTA #RegulatoryAffairs #EvidenceSynthesis

Bone-healing NMA separates modality effects from functional recovery. https://www.mattheneus.com/editorial/pubmed-electrical-stimulation-bone-healing-network-meta-analysis-modality-ranking-2026-10-07 #HTA #NMA #EvidenceSynthesis

Risk misclassification can reshape the value case for risk-stratified breast screening. https://www.mattheneus.com/editorial/risk-stratified-breast-screening-misclassification-capacity-cost-effectiveness-2026-10-01 #HTA #HealthEconomics #EvidenceSynthesis

Intelligent-knife evidence now needs to connect diagnostic accuracy with surgical and patient outcomes. https://www.mattheneus.com/editorial/pubmed-intelligent-knife-cancer-surgery-diagnostic-outcomes-evidence-gap-2026-10-06 #HTA #EvidenceSynthesis #HealthEconomics

When can observational evidence credibly join randomised trials in one synthesis? A practical look at the decision. https://www.mattheneus.com/editorial/cochrane-grade-observational-randomised-evidence-integration-2026-10-05 #HTA #EvidenceSynthesis #RWE

Patient-relevant outcomes reach HTA decisions through four practical stages, from question framing to accountable use. https://www.mattheneus.com/editorial/ispor-patient-relevant-outcomes-four-stage-hta-framework-2026-10-06 #HTA #HealthEconomics #EvidenceSynthesis

Three reviews reveal a critical evidence gap in adult type 1 diabetes care in humanitarian settings. #HTA #EvidenceSynthesis #HealthEconomics https://www.mattheneus.com/editorial/pubmed-type1-diabetes-humanitarian-settings-evidence-gap-systematic-reviews-2026-10-06

A 90-trial menopause review separates symptom effects from economic value. #HTA #EvidenceSynthesis #HealthEconomics https://www.mattheneus.com/editorial/acp-menopause-vasomotor-pharmacologic-treatment-systematic-review-value-2026-10-06

A five-domain evidence map can make HTA planning more systematic and decision-ready. #HTA #EvidenceSynthesis #Pharma https://www.mattheneus.com/editorial/htai-five-domain-evidence-map-hta-planning-2026-10-05

#CochraneDaily
Just published!
Systematic review of studies of using large language models for screening articles for inclusion in systematic reviews concludes that #LLM might substantially reduce the time needed for this key task.
onlinelibrary.wiley.com/doi/abs/10.1...
#EvidenceSynthesis #AI

A shared AI glossary can give evidence teams a clearer vocabulary for validation and governance. https://www.mattheneus.com/editorial/htai-generative-artificial-intelligence-glossary-validation-vocabulary-2026-10-05 #HTA #EvidenceSynthesis #RegulatoryAffairs