@scienceofpd.bsky.socialUsing human dorsolateral prefrontal cortex samples from 1,494 donors, researchers generate a single-cell transcriptomic atlas comprising over 6.3 million individual nuclei. Donors include #Alzheimers & #Parkinsons cases ("the PsychAD cohort")
www.nature.com/articles/s41...
@scienceofpd.bsky.socialSeed amplification analysis of released a-synuclein strains from #Parkinsons-patient derived neurons (iPD, GBA1 N370S, LRRK2 G2019S & SNCA A53T) reveals genotype-specific cellular responses differentially shape the structural properties of released α-syn
www.frontiersin.org/journals/agi...
@scienceofpd.bsky.socialResults of a 1-year randomized, placebo-controlled pilot study of oral N-acetylcysteine (2x daily) or placebo in 42 people with #Parkinsons have been published. A smaller increase in total UPDRS & a smaller decline in striatal TRODAT binding vs placebo
link.springer.com/article/10.1...
@scienceofpd.bsky.socialA retrospective case-control analysis of Type 1 Gaucher disease patients within a single academic clinic from 2010 to 2020 finds considerable variability in GD- #Parkinsons among GD1 individuals & suggest that GD1 patients may have⬆️risk of GD-PD<age of 50
www.sciencedirect.com/science/arti...
@scienceofpd.bsky.socialAnalysing 5.3M adults in the Korean National Health Insurance Database (2010–2019), researchers find that long-term exposure to PM2.5 & O3 was associated with a small but statistically signif. increase in #Parkinsons incidence in older adults
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
@chemcenterbio.bsky.socialThe Holy Grail of Brain Repair: Which BDNF Booster Wins?
Analyze how Semax and elite BDNF peptides stimulate rapid neuroplasticity in research models for animals.
#peptdes #AlzheimersResearch #autismresearch #parkinsons #alsresearch
@worldpdcongress.bsky.socialWe’re thrilled to welcome Northwest Parkinson's Foundation as a WPC Champion Partner! 💙 #WPC2029 #WorldParkinsonCongress #Parkinsons
@longevitytech.bsky.socialNKGen presented new clinical data on troculeucel’s potential in Alzheimer’s, Parkinson’s and frontotemporal dementia.
Link as first comment.
@worldpdcongress.bsky.social🎶 The Parkinson Battle Hymn is raising awareness through music. https://youtu.be/cRE6PwIMIZQ?si=C9NYZYXnRbNvgJST
Learn about the Sept. 29 benefit concert organized by Professor Bas Bloem supporting Parkinson’s research where this song will be featured. www.sedv.nl/benefiet
@scienceofpd.bsky.socialPlasma samples (n = 504) analysed using SomaScan, finds lysosomal expression scores discriminate #Parkinsons from controls & associated with disease severity. SUMF1 & ARRDC3 emerged as blood-based biomarkers for PD
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
@scienceofpd.bsky.socialMetavallon backs #Parkinsons biotech Anacalypsis to help finance the advancement of AT001, a LRRK2–FADD interaction disruptor, which is being developed for #Parkinsons
www.biospace.com/press-releas...
@scienceofpd.bsky.socialNew review summarizes the current understanding of the biological mechanisms linking GBA1 to #Parkinsons, including both loss-of-function & gain-of-function hypotheses; Also clinical & translational advances
academic.oup.com/brain/advanc...
@scienceofpd.bsky.socialThe results of the PARKEX study have been published. This was a trial exploring the effects of basic &dual-task training programs on physical function in #Parkinsons
journals.plos.org/plosone/arti...
@scienceofpd.bsky.socialCognition endpoints for #Parkinsons: Researchers provide a roadmap for developing patient-focused assessment tools to accelerate drug development
journals.sagepub.com/doi/10.1177/...
@scienceofpd.bsky.socialResearchers present BenSParX: A robust explainable machine learning framework for #Parkinsons detection from Bengali conversational speech
www.sciencedirect.com/science/arti...
@worldpdcongress.bsky.social💙 10 years ago, 4,550+ people from 67 countries came together in Portland for WPC 2016. What a Congress! #WPC2016 #Parkinsons #WorldParkinsonCongress
@scienceofpd.bsky.socialThe MJFF grant will support development of a potential disease-modifying treatment for prodromal #Parkinsons, while PUK's funding will further explore the link between enhanced slow-wave sleep & glymphatic flow - the brain’s natural waste-clearance mechanism
@scienceofpd.bsky.socialAstronauTx has been awarded funding from the Michael J Fox Foundation & @parkinsons.org.uk to explore sleep-based approaches for #Parkinsons
astronautx.bio/astronautx-a...
@scienceofpd.bsky.socialBiology-first AI drug discovery company, Lunai Bioworks announces an exclusive worldwide license & collaboration agreement with Tanaist that adds human cellular phenotyping to their #Parkinsons platform
ir.lunaibioworks.com/news/news-de...
@brainsupportnet.bsky.socialParkinson's Risk and Carbon Monoxide: What a New Study Found'
Analysis offers surprising twist to the smoking-Parkinson's puzzle
Read at MedPageToday: www.medpagetoday.com/neurology/pa...
