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@aibusinesslens.bsky.socialOct 10, 2026, 2:00 PM

The teen mode mimicked human emotions while directing users to crisis hotlines less often than the standard model.

Public Health · Engadget
#PublicHealth #MedSky

@shihcheng.bsky.socialOct 10, 2026, 2:00 PM

Rituximab vs Ocrelizumab in MS: In a 24-month trial with 3:2 randomization, 23% had no new T2 lesions on MRI. PMID:42384870, N Engl J Med 2026, @NEJM https://doi.org/10.1056/NEJMoa2600993 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

@currentmedscience.bsky.socialOct 10, 2026, 12:30 PM

Early-onset #diabetes across generations may have a genetic basis.

This study identifies #PathogenicVariants in HNF1A, PDX1, KCNJ11 and WFS1, supporting precision diagnosis and treatment.
#currentmedicalscience: doi.org/10.1007/s115...

#GeneticCounseling #medsky

Clinical and Genetic Characteristics of Patients with Early-Onset Diabetes Involving at Least Two Consecutive Generations: Whole-Exome Sequencing in Probands from 25 Pedigrees
@medicine.stitches.todayOct 10, 2026, 12:26 PM

Ovarian Cancer Guideline Update: Prioritize Platinum-Based Regimens for Recurrence, with Mirvetuximab for Resistant Cases

by Lesnock JL, Temin S (...) Scalici JM et 14 al. in J Clin Oncol #MedSky

👉 get more here

📖 read the article: https://ascopubs.org/doi/10.1200/JCO-26-01591

@shihcheng.bsky.socialOct 10, 2026, 12:00 PM

A study reveals that parvalbumin-expressing inhibitory neurons from the basal forebrain are crucial for sustaining attention, countering prior beliefs about cholinergic neurons. PMID:42349384, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600646X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

@thelancetendo.bsky.socialOct 10, 2026, 11:53 AM

Further research is needed to identify the determinants of #survival and #healthy #ageing among people with type 1 #diabetes, including potential differences between youth-onset and adult-onset disease www.thelancet.com/journals/lan...
#T1D #olderadults #aging

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 10, 2026, 11:42 AM

Increasing evidence indicates that #progression & #complications [of type 2 #diabetes] might be modifiable, but the absence of a core outcome set for disease modification limits trial design & intervention comparison www.thelancet.com/journals/lan...
#disease-modifying therapies

#MedSky #EndoSky

@thelancetendo.bsky.socialOct 10, 2026, 11:35 AM

The global prevalence of #diabetes is rising rapidly, with the steepest increases and greatest unmet need occurring in low-income and middle-income countries.

Read more in this global perspective on the role of #primary #care www.thelancet.com/journals/lan... #T2D #LMICs

#MedSky #EndoSky

@baladocritique.bsky.socialOct 10, 2026, 11:11 AM

“Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.”
Publié ce jour dans @thelancet.com.
#MedSky #EndoSky
www.thelancet.com/journals/lan...

@shihcheng.bsky.socialOct 10, 2026, 11:00 AM

Breakthrough: Efficient intracellular assembly of artificial enzymes enables enantioselective Mannich reactions in cells. Revolutionizing biocatalysis with abiological cofactors! 🌟 PMID:42386753, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-75059-9 #Medsky #Pharmsky #RNA #ASHG 🧪

@shihcheng.bsky.socialOct 10, 2026, 10:00 AM

Designs quasisymmetric two-component protein cages using computational strategies inspired by icosahedral viral capsids. Complex nanoscale architecture unlocked! PMID:42162421, Nature 2026, @Nature https://doi.org/10.1038/s41586-026-10464-0 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

@shihcheng.bsky.socialOct 10, 2026, 9:00 AM

Deep-Phase, a neural network, deciphers changes in biomolecular condensate morphology due to drugs, linking molecular interactions to mesoscale organization. PMID:42242225, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00569-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

@trishaelliott.bsky.socialOct 10, 2026, 8:52 AM

What does it mean to recover from Long Covid?

Here in the @bmj.com from a few weeks ago, Charlie Dennis, a final year student and @nisreenalwan.bsky.social write about how we’ve still not got a good definition of this, and that is hampering progress.

Link: www.bmj.com/content/393/...

#MedSky

Except from BMJ article: Defining recovery is essential for research, clinical care, and patient experience, say Charlie Dennis and Nisreen A Alwan If you have long covid, how can you tell if you have fully recovered? Six years of evidence and collective lived experience show us that this is not an easy question to answer. Yet if we do not define recovery, we cannot properly count the number of people living with long covid, and its present and future impact on the population’s wellbeing, economic productivity, and health systems. Long covid remains a substantial global health problem. A recent report estimated that this condition will cost countries in the Organisation for Economic Cooperation and Development (OECD) $11bn (£8.3bn; €9.6bn) a year in healthcare costs over the next decade. The projected economic costs are $135bn a year.Second page of article.
@cbarbermd.bsky.socialOct 10, 2026, 8:40 AM

enrollment begins.
www.nytimes.com/2026/10/09/b...
#BlueSky #MedSky #NirseSkt #IMSky #LawSky

@trishaelliott.bsky.socialOct 10, 2026, 8:39 AM

You are absolutely right.

Having worked in the NHS for four decades, we remain spectacularly bad at treating and caring for people with #mecfs and in fact many long term conditions that medical science doesn’t fully understand.

#MedSky

@trishaelliott.bsky.socialOct 10, 2026, 8:31 AM

I liked this piece from @johnlauner.bsky.social on the concert of General Practice as “mosaic care”.

#MedSky

@haemnet.bsky.socialOct 10, 2026, 8:30 AM

The#WorldMentalHealthDay theme "Lived experiences heard: Real voices, real change" speaks to us. In our research, people impacted by #bleedingdisorders tell us they need more #mentalhealth support. #Livedexperience can inform positive change in policies, services & care.

#HemeSky #MedSky

@trishaelliott.bsky.socialOct 10, 2026, 8:26 AM

I think @scarlettmcnally.bsky.social is right in her assessment here.

Promoting walking for everyone is a good thing, but is this really the best way to get everyone more active?

From the @bmj.com back in the summer, but I’m just catching up now.

Link: www.bmj.com/content/394/...

#MedSky

Excerpt: NHS England recently announced plans to launch a new incentive scheme that will reward people who achieve 30 minutes of walking a day, adding up to a “marathon in a month.” I see several weaknesses in this plan. A quarter of the adult population do less than 30 minutes of exercise in a whole week. This is the group who stand to gain the biggest health improvements from any exercise, but they are unlikely to start doing 30 minutes of walking every day. I worry that the new incentive, and the funding, effort, and media outreach behind it, will attract only the people who are active already, further widening health inequalities. Evidence suggests that incentive schemes lead to minimal long term behaviour change, so this scheme won’t tackle deep rooted cultural and behavioural determinants of inactivity.There is a science to behaviour change. Capability, opportunity, and motivation are required to change behaviour. A third of adults claim that they don’t have the opportunity to be active because of time constraints, safety concerns, or where they live.
@shihcheng.bsky.socialOct 10, 2026, 8:00 AM

Study reveals 1,000× sequencing of 311 brain samples shows somatic variants in cancer genes enrich AD microglia, linking clonal hematopoiesis to neuroinflammation. PMID:42019491, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00341-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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