@stephanhacker2.bsky.socialA true firework of covalent drug discovery to close out the Covalent Modulation in Drug Discovery Conference #CovModDrugDiscov!
Ed Tate presented a variety of exciting projects of his group.
#CovalentInhibitor #DrugDiscovery #ChemSky #ChemBio #Science
@alvascience.bsky.socialChemical data, a modelling question or a workflow to improve?
Alvascience offers cheminformatics consulting, QSAR modelling and custom scientific software development.
Tell us about your project: alvascience.com/services/
@stemfem.bsky.social10/8/1872 — b. Mary Engle Pennington, American bacteriological chemist, refrigeration engineer, author. She revolutionized methods of storing and transporting foods; an authority on the preservation of #food with refrigeration #womenshistory #WomenInSTEM #ChemSky #BioSky #SciSky #HistSci #FoodSky
@rsc.orgLooking for an industry placement?
Join our latest ChemCareers webinar on Finding and applying for an industry placement and learn how to find chemistry placements, strengthen your applications and stand out to employers.
Register now: https://rsc.li/4rNEKPr
@stephanhacker2.bsky.socialInteresting talk by Michael Bodnarchuk from @astra-zeneca.bsky.social at #CovModDrugDiscov.
He talked about the use of computational tools to discover covalent, brain-penetrant KRAS G12C inhibitors.
#CovalentInhibitor #DrugDiscovery #ChemSky #ChemBio #Science
@rsc.orgJoin our new ChemSpider webinar, sponsored by Merck KGaA, JMP and CDD, to empower your data management, discover the importance of good data management, touch relevant standards and hear from expert speakers.
Register now: https://rsc.li/4iUY7no
@stephanhacker2.bsky.socialExciting talk by Yoav Shamir from the group of Nir London at #CovModDrugDisvov!
He talked about cofolding in Alphafold3 to identify #CovalentInhibitors with novel structures for BTK.
#DrugDiscovery #Kinase #ChemSky #ChemBio #Science
@britpharmsoc.bsky.social
@cenmag.bsky.socialScientists unveiled two intermediate structures formed during light-induced trans-cis isomerization of azobenzene, a common molecular photoswitch, using a technique called femtosecond time-resolved X-ray liquidography (TRXL).
#chemsky 🧪
@cenmag.bsky.socialAs space agencies prepare to turn brief excursions into long-term stays on the moon and Mars, chemistry shifts from a backstage helper to a leading role.
@arbitraryeffect.bsky.socialThanks @dalmeet.bsky.social for covering TRACES in @cenmag.bsky.social. Short version: we gave 30 AI models 42 truly awful papers, and asked them to extend the work.
How awful? Magnetized water awful. Cold fusion awful.
The LLMs cheerfully helped, more than 93% of the time.
@kohulanr.bsky.socialOrthonym v1.0.5 is now on conda-forge 🎉
Verified IUPAC names, by rule. OPSIN reads back every name; if it doesn't match, Orthonym declines.
🌐 conda install -c conda-forge orthonym
#ChemSky #Cheminformatics #OpenScience #FAIR #Chemistry #OpenSource #CompChem
@stephanhacker2.bsky.socialInteresting talk by Chloe Oxford from GSK at #CovModDrugDiscov.
She talked about a MALDI-TOF-MS-based assay to characterize the binding of #CovalentInhibitors to challenging proteins with resolution of the binding site.
@chemistryworld.comRebecca Trager takes a deeper dive into the French and Japanese chemists who have just shared this year’s chemistry Nobel prize for their discovery of non-linear effects and autocatalysis in asymmetric organic synthesis.
@michaljuricek.bsky.socialCongratulations to Andrej Vladimir Riedi for the Best student performance at my first-year undergrad organic chemistry course CHE102 - Bond with the molecules of life!! 👏👏👏
@chem.uzh.ch @chemsky.bsky.social #ChemSky #studentlife
@cenmag.bsky.socialA bipartisan group of senators has introduced legislation to tackle longstanding woes with the federal permitting process for major energy and infrastructure projects—and chemical and other industry players are voicing support for the effort.
#chemsky 🧪
@aletheakontis.comHappy #WorldOctopusDay 🐙!
Did you know that in Thieftess, selkies bleed teal, trolls bleed violet & siren hair turns red when they drink blood because the follicles are hollow like a polar bear?
Did you know I majored in Chemistry?
#chemsky #Booksky #MarineScience
aletheakontis.com/2026/06/thie...
@tenuretracker.bsky.socialHarvard University (@harvard.edu) is hiring:
Postdoctoral Position in Electrochemistry of Layered Thin-Film Oxides
@pwk2024.bsky.socialGehringer & Heppner, In Pursuit of Enduring Inactivation: A Perspective on the Development and Study of Irreversible-Covalent Inhibitors. Biochemistry 2026 #biochem #biophys #MedChem #ChemBiol #OpenAccess #chemsky 🧪
doi.org/10.1021/acs....
@stephanhacker2.bsky.socialInteresting talk by Federica Raguseo at #CovModDrugDiscov.
She talked about a phenotype-first approach to covalent drug discovery on the example of TYMS.
www.biorxiv.org/content/10.6...
#CovalentInhibitor #DrugDiscovery #ChemSky #ChemBio #Science
@britpharmsoc.bsky.social
@icdd.bsky.socialToday is the last day to apply for the 2027 Ludo Frevel Crystallography Scholarship! The 2027 scholarship awards will be $3,000 each and include a one-year subscription to the PDF-5+ 2027 database. Apply now! www.icdd.com/ludo-frevel-scholarship #chemsky
