@epigenometech.bsky.socialEpigenetics Update - HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling u.epigenome.us/DkINkLJD
Yu Zhang, Yichuan Xiao, & Xianling Cong in Nat Commun
#Epigenetics #Chromatin #Progeria #Aging
---
Empower your research; epigenometech.com
@epigenometech.bsky.socialEpigenetics Update - 3D chromatin remodeling during domestication defines novel targets for crop improvement u.epigenome.us/WSBXe75B
Xianlong Zhang and Maojun Wang (Shihezi University) in Cell
#Epigenetics #Chromatin #Crops #Domestication
---
Discover the breakthrough at epigenometech.com
@epigenometech.bsky.socialEpigenetics Update - Cohesin reshapes replication fork contacts to aid fork slowing and reversal u.epigenome.us/slt1VlCs
daniga90.bsky.social, Ana Losada, and lopeslab.bsky.social in nature.com
#Epigenetics #Cohesin #Chromatin #Forks
---
Hi-res insights without cell sorting; epigenometech.com
@kubasawicki.bsky.socialHow do early land plants switch between water and land? 🌿💧
In our new study in Frontiers in Plant Science, we paired SBS with @nanoporetech.com sequencing to explore alternative splicing and 5mC DNA methylation in Riccia fluitans:
@epigenometech.bsky.socialEpigenetics Update - Viral mimicry escape as a necessary feature of malignant transformation www.nature.com/articles/s41...
Daniel De Carvalho (uhn.ca / utoronto.ca) in Nature Reviews Cancer
#Epigenetics #ViralMimacry #Cancer
---
Cancer, immunology, and aging; epigenometech.com
@epigenometech.bsky.socialEpigenetics Update - Histone H2B monoubiquitination drives sexual commitment in malaria parasites www.nature.com/articles/s41...
Jing Yuan/Jian Li and Qingfeng Zhang in Nature Microbiology
#Epigenetics #Malaria #Chromatin #HistoneH2B
---
Empower your research at epigenometech.com
@epigenometech.bsky.socialEpigenetics Update - Structure-guided discovery and engineering of miniature CRISPR-Cas12m for epigenome editing u.epigenome.us/EH7zr6pD
Kuanhui Xiang, Lin Bai, and Kailong Li (pku1898.bsky.social) in NSMB
#Epigenetics #CRISPR #EpigenomeEditing
---
Gain deeper insights; epigenometech.com
@epigenometech.bsky.socialEpigenetics Update - Rapamycin targetome mining identifies RBBP7 as a druggable epigenetic vulnerability in hepatocellular carcinoma u.epigenome.us/jje91JhP
Bing Shan & Yaoyang Zhang (CAS) in Cell Chemical Biology
@epigenometech.bsky.socialEpigenetics Update - 5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia u.epigenome.us/MBe0Tv0n
Mingjiang Xu and Chuan He in Molecular Cell
#Epigenetics #Chromatin #caRNAs #Leukemia
---
Cancer, immunology, and aging; epigenometech.com
@sip-com-acpe.bsky.socialTitle: Giving low-income mothers a monthly cash stipend slows their children’s biological aging
Link: ift.tt/Tz7Z5A6
#epigenetics #poverty #childdevelopment #psychotherapy #publichealth
@epigenometech.bsky.socialEpigenetics Update - Type 1 interferon perturbates clonal competition by reshaping human blood development u.epigenome.us/BzWFNOBt
Ronald Hoffman and Anna S. Nam (weillcornell.bsky.social) in Nature Genetics
@epigenometech.bsky.socialEpigenetics Update - Cryo-EM structure, enzymatic activity and genome targeting of canonical PRC1 u.epigenome.us/xluYsD5s
Jacques Bonnet and Jürg Müller (mpibiochem.bsky.social) in NSMB
#Epigenetics #PRC1 #Chromatin
---
Discover the breakthrough at epigenometech.com
@proteinimaging.bsky.socialHere you can see a cryoEM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome (PDB code: 9Y4P)
Rendering by Francisco J. Enguita made with #ProteinImager
#SciArt #molecularart #dna #genome #epigenetics #methylation #methyltransferase #nucleosome
@epigenometech.bsky.socialEpigenetics Review - A practical guide to studying genome function using single-molecule genomics www.nature.com/articles/s41...
This Expert Recommendation article provides a guide for adopting single-molecule genomics and outlines best practices
---
@gmj-georgia.bsky.social📊 New research reveals: training breaks aren't as costly as athletes fear. Three studies show DNA methylation patterns preserve fitness adaptations weeks afte… #Detraining #Epigenetics #Exercisescience #Musclephysiology #Sportsmedicine #Detraining #Epigenetics #Exercisescience #Musclephysiology…
@currentmedscience.bsky.socialThis study summarizes the role of #TranscriptionFactors in #ALD pathology—from lipid metabolism to ER stress—and highlights promising targeted therapies for ALD treatment. #medsky
Read more: doi.org/10.1007/s115...
@tenuretracker.bsky.socialAarhus University (@au.dk) is hiring:
Postdoctoral Position in Chromatin Biology and Epigenetic Gene Regulation
@wimi-bio-tech.bsky.social#PekingUniversity researchers discovered PmCas12m—a naturally nuclease-dead miniature Cas nuclease—and engineered #xCas12m (581 aa), enabling #single-AAV packaging of xCas12m-CRISPRoff for durable in vivo HBV epigenetic silencing in mice. 🧬🤖 #Epigenetics #CRISPRoff #GeneTherapy #HBV
@4quazulu.bsky.social
