@epigenometech.bsky.socialEpigenetics Update - 5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia u.epigenome.us/MBe0Tv0n
Mingjiang Xu and Chuan He in Molecular Cell
#Epigenetics #Chromatin #caRNAs #Leukemia
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Cancer, immunology, and aging; epigenometech.com
@sip-com-acpe.bsky.socialTitle: Giving low-income mothers a monthly cash stipend slows their children’s biological aging
Link: ift.tt/Tz7Z5A6
#epigenetics #poverty #childdevelopment #psychotherapy #publichealth
@epigenometech.bsky.socialEpigenetics Update - Type 1 interferon perturbates clonal competition by reshaping human blood development u.epigenome.us/BzWFNOBt
Ronald Hoffman and Anna S. Nam (weillcornell.bsky.social) in Nature Genetics
@epigenometech.bsky.socialEpigenetics Update - Cryo-EM structure, enzymatic activity and genome targeting of canonical PRC1 u.epigenome.us/xluYsD5s
Jacques Bonnet and Jürg Müller (mpibiochem.bsky.social) in NSMB
#Epigenetics #PRC1 #Chromatin
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Discover the breakthrough at epigenometech.com
@proteinimaging.bsky.socialHere you can see a cryoEM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome (PDB code: 9Y4P)
Rendering by Francisco J. Enguita made with #ProteinImager
#SciArt #molecularart #dna #genome #epigenetics #methylation #methyltransferase #nucleosome
@epigenometech.bsky.socialEpigenetics Review - A practical guide to studying genome function using single-molecule genomics www.nature.com/articles/s41...
This Expert Recommendation article provides a guide for adopting single-molecule genomics and outlines best practices
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@gmj-georgia.bsky.social📊 New research reveals: training breaks aren't as costly as athletes fear. Three studies show DNA methylation patterns preserve fitness adaptations weeks afte… #Detraining #Epigenetics #Exercisescience #Musclephysiology #Sportsmedicine #Detraining #Epigenetics #Exercisescience #Musclephysiology…
@currentmedscience.bsky.socialThis study summarizes the role of #TranscriptionFactors in #ALD pathology—from lipid metabolism to ER stress—and highlights promising targeted therapies for ALD treatment. #medsky
Read more: doi.org/10.1007/s115...
@tenuretracker.bsky.socialAarhus University (@au.dk) is hiring:
Postdoctoral Position in Chromatin Biology and Epigenetic Gene Regulation
@wimi-bio-tech.bsky.social#PekingUniversity researchers discovered PmCas12m—a naturally nuclease-dead miniature Cas nuclease—and engineered #xCas12m (581 aa), enabling #single-AAV packaging of xCas12m-CRISPRoff for durable in vivo HBV epigenetic silencing in mice. 🧬🤖 #Epigenetics #CRISPRoff #GeneTherapy #HBV
@doctoryemi.bsky.socialYour environment can impact your DNA, even before birth. Lifestyle choices can 'gum up' your genes and be passed to offspring. Take control of your health.
@epigenometech.bsky.socialDownload our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
@epigenometech.bsky.socialEpigenetics Update - Epigenetic repression of IL-1β by C1QBP restricts Dectin-1-mediated host defense against murine invasive candidiasis u.epigenome.us/mQl9jwo4
Yebo Gu & Xin-Ming Jia (Tongji University) in Nat Commun
@epigenometech.bsky.socialEpigenetics Update - Mitochondrial ATP promotes T cell differentiation through chromatin accessibility u.epigenome.us/AwFnxEpF
Charles Ng & Craig B. Thompson (mskcancercenter.bsky.social) in Cell
#Epigenetics #Mitochondria #Chromatin
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Cancer, immunology, and aging; epigenometech.com
@epigenometech.bsky.socialEpigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis
@epigentek.bsky.socialThe MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit offers a fast, sensitive, colorimetric workflow for quantifying 5-mC across a wide range of DNA samples.
#DNAMethylation #5mC #Epigenetics #ELISA #MolecularBiology
@pablonavarrolab.bsky.social🧬 How do cells remember?
Join us in beautiful Baeza 🇪🇸 for Transcriptional Memory in Health and Disease, 20–22 October.
💥 Young scientists: €250, including meals!
📢 Deadline extended to 27 September — you can do this!
@epigenometech.bsky.socialEpigenetics Update - A stem-like chromatin program in small-cell lung cancer is associated with poor outcomes after chemoimmunotherapy u.epigenome.us/TJD2LY55
Anish Thomas (NCI, NIH) in Cell Reports Medicine
#Epigenetics #StemCells #Cancer #SCLC #Chemoimmunotherapy
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@imprs-lm.bsky.social🔍 for a #PhDposition in #chemicalbiology?
👉 Apply to the Summerer lab @imprs-lm.bsky.social to decode and redesign the epigenetic landscape that regulates gene expression, using protein evolution, biomacromolecular chemistry, and genetic code expansion.
#Epigenetics #GenomeEngineering
@4quazulu.bsky.social
